| Specifications | |
|---|---|
| Assay (complexometric; calculated on dried substance) | 99.0 - 101.0 % |
| Assay (complexometric; calculated as dihydrate) | 99.0 - 101.0 % |
| Identity (IR-spectrum) | passes test |
| Identity (Complexation) | passes test |
| Identity (Sodium) | passes test |
| Appearance | passes test |
| Appearance of solution (50 g/l; water) | passes test |
| pH (10 g/l, water) | 4.3 - 4.7 |
| pH (50 g/l; water) | 4.0 - 5.5 |
| Cyanide (CN) | ≤ 1 ppm |
| Heavy metals (as Pb) | ≤ 10 ppm |
| As (Arsenic) | ≤ 1 ppm |
| Ca (Calcium) | passes test |
| Fe (Iron) | ≤ 5 ppm |
| Nitrilotriacetic acid (HPLC) | ≤ 0.1 % |
| Methanol (HS-GC) | ≤ 3000 ppm |
| Other residual solvents (Ph.Eur./USP/ICH) | passes test |
| Loss on drying (150 °C; 6 h) | 8.7 - 11.4 % |
| Sulfated ash (600 °C) | 37.0 - 39.0 % |
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Key Spec Table
| CAS # | EC Number | Hill Formula | Chemical Formula | Molar Mass | Grade Value |
|---|---|---|---|---|---|
| 6381-92-6 | 205-358-3 | C₁₀H₁₄N₂Na₂O₈*2H₂O | C₁₀H₁₄N₂O₈*2Na*2H₂O | 372.24 g/mol | Ph Eur,BP,JP,USP |
| Description | |
|---|---|
| Catalogue Number | 108421 |
| Synonyms | Disodium dihydrogen ethylenediaminetetraacetate, Ethylenediaminetetraacetic acid disodium salt |
| Product Information | |
|---|---|
| CAS number | 6381-92-6 |
| EC number | 205-358-3 |
| Grade | Ph Eur,BP,JP,USP |
| Hill Formula | C₁₀H₁₄N₂Na₂O₈*2H₂O |
| Chemical formula | C₁₀H₁₄N₂O₈*2Na*2H₂O |
| Molar Mass | 372.24 g/mol |
| HS Code | 2922 49 85 |
| Structure formula Image | |
| Applications | |
|---|---|
| Application | Titriplex® III (ethylenedinitrilotetraacetic acid disodium salt dihydrate) suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP. CAS No. 6381-92-6, EC Number 205-358-3. MSDS (material safety data sheet) or SDS here. |
| Physicochemical Information | |
|---|---|
| Melting Point | 110 °C Elimination of water of crystallisation |
| pH value | 4 - 5 (50 g/l, H₂O, 20 °C) |
| Bulk density | 700 kg/m3 |
| Solubility | 100 g/l |
| Toxicological Information | |
|---|---|
| LD 50 oral | LD50 Rat > 2000 mg/kg |
| Safety Information according to GHS | |
|---|---|
| Hazard Pictogram(s) |   |
| Hazard Statement(s) | H332: Harmful if inhaled. H373: May cause damage to organs through prolonged or repeated exposure if inhaled. |
| Precautionary Statement(s) | P314: Get medical advice/ attention if you feel unwell. |
| RTECS | AH4410000 |
| Storage class | 10 - 13 Other liquids and solids |
| WGK | WGK 2 water endangering |
| Disposal | 3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. |
| Safety Information | |
|---|---|
| Hazard Symbols |  Harmful |
| R Phrase | R 20-48/20 Harmful by inhalation.Harmful: danger of serious damage to health by prolonged exposure through inhalation. |
| Storage and Shipping Information | |
|---|---|
| Storage | Storage temperature: no restrictions. |
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