| Description | |
|---|---|
| Catalogue Number | 102735 |
| Synonyms | Cys, L-Cysteinium Chloride Monohydrate, L-Cysteine Hydrochloride, Monohydrate |
| Product Information | |
|---|---|
| CAS number | 7048-04-6 |
| EC number | 200-157-7 |
| Grade | Ph Eur,USP |
| Hill Formula | C₃H₈ClNO₂S * H₂O |
| Molar Mass | 175.64 g/mol |
| HS Code | 2930 90 16 |
| Structure formula Image | |
| Physicochemical Information | |
|---|---|
| Melting Point | 168 - 170 °C |
| pH value | 0.8 - 1.2 (100 g/l, H₂O, 20 °C) |
| Bulk density | 780 kg/m3 |
| Solubility | 650 g/l |
| Safety Information according to GHS | |
|---|---|
| RTECS | HA2285000 |
| Storage class | 10 - 13 Other liquids and solids |
| WGK | WGK 1 slightly water endangering |
| Disposal | 3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. |
| Storage and Shipping Information | |
|---|---|
| Storage | Store at +5°C to +30°C. |
| Specifications | |
|---|---|
| Assay (iodometric, calc. on dried substance) | 98.5 - 101.0 % |
| Identity (IR-spectrum) | passes test |
| Identity (Chloride) | passes test |
| Appearance | white to almost white crystalline powder or colorless crystals |
| Appearance of solution (25 g/l, water) | clear and not more intense in color than reference solution BY₆ |
| Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance) | +5.5 to +7.0 |
| Spec. rotation (α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance) | +5.7 to +6.8 |
| Sulphate (SO₄) | ≤ 300 ppm |
| Heavy metals (as Pb) | ≤ 10 ppm |
| Fe (Iron) | ≤ 20 ppm |
| Related Compounds, total (TLC) | ≤ 0.5 % |
| Ninhydrin-positive substances (LC) (impurity A (570 nm)) | ≤ 0.5 % |
| Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity) | ≤ 0.2 % |
| Ninhydrin-positive substances (LC) (ammonium (570 nm)) | ≤ 0.02 % |
| Ninhydrin-positive substances (LC) (total impurities) | ≤ 1.0 % |
| Residual solvents (ICH Q3C) | excluded by manufacturing proces |
| Sulfated ash (600 °C) | ≤ 0.1 % |
| Loss on drying (Vacuum < 0.7 kPa, P₂O₅, 24 h) | 8.0 - 12.0 % |
| Bacterial endotoxins | ≤ 6.0 I.U./g |
| Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*). | |
| Corresponds to Ph. Eur., USP. | |
