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Dichloromethane

suitable for use as excipient
EMPROVE®
exp Ph Eur,BP,NF.
CAS 75-09-2,
chemical formula CH₂Cl₂
Code: 1060492500
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suitable for use as excipient EMPROVE® exp Ph Eur,BP,NF. CAS 75-09-2, chemical formula CH₂Cl₂

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
75-09-2 200-838-9 CH₂Cl₂ CH₂Cl₂ 84.93 g/mol Ph Eur,BP,NF
Description
Catalogue Number 106049
Synonyms DCM, Methylene chloride, Methylene dichloride
Description Dichloromethane
Product Information
CAS number 75-09-2
EC index number 602-004-00-3
EC number 200-838-9
Grade Ph Eur,BP,NF
Hill Formula CH₂Cl₂
Chemical formula CH₂Cl₂
Molar Mass 84.93 g/mol
HS Code 2903 12 00
Structure formula Image
Applications
Application Dichloromethane suitable for use as excipient EMPROVE® exp Ph Eur,BP,NF. CAS 75-09-2, chemical formula CH₂Cl₂. Dichloromethane MSDS or SDS, and related info below.
Physicochemical Information
Boiling point 40 °C (1013 hPa)
Density 1.33 g/cm3 (20 °C)
Evaporation number 1.9
Explosion limit 13 - 22 %(V)
Ignition temperature 605 °C DIN 51794
Melting Point -95 °C
Vapor pressure 475 hPa (20 °C)
Solubility 20 g/l
Toxicological Information
LD 50 oral LD50 Rat 1600 mg/kg
LD 50 dermal LD50 Rat > 2000 mg/kg
Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s) H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H336: May cause drowsiness or dizziness.
H351: Suspected of causing cancer.
H373: May cause damage to organs through prolonged or repeated exposure.
Precautionary Statement(s) P281: Use personal protective equipment as required.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P314: Get medical advice/ attention if you feel unwell.
RTECS PA8050000
Storage class 6.1 D Non combustible, acute toxicity cat. 3 / toxic or substances with chronic effects
WGK WGK 2 water endangering
Disposal 2
Organic halogenated solvents and solutions of organic halogen-containing substances: For strongly contaminated or mixed halogenated solvents container B: Caution: Do not use aluminium containers; in addition, in the case of water-containing chlorinated waste materials do not use stainless-steel containers (danger of leaks caused by corrosion).
Safety Information
Hazard Symbols Harmful
Categories of danger carcinogenic
R Phrase R 36/37/38-40-67
Irritating to eyes, respiratory system and skin.Limited evidence of a carcinogenic effect.Vapours may cause drowsiness and dizziness.
S Phrase S 3-36/37
Keep in a cool place.Wear suitable protective clothing and gloves.
Storage and Shipping Information
Storage Store at +15°C to +25°C.
Transport Information
Declaration (railroad and road) ADR, RID UN 1593 , 6.1, III
Declaration (transport by air) IATA-DGR UN 1593 , 6.1, III
Declaration (transport by sea) IMDG-Code UN 1593 , 6.1, III, Segregation Group: 10 (Liquid halogenated hydrocarbons)
Specifications
Purity (GC) ≥ 99.0 %
Identity (IR) conforms
Appearance of the substance conforms
Acidic substances conforms
Acidity (HCl) ≤ 0.001 %
Density (d 20 °C/20 °C) 1.320 - 1.332
Density (d 25 °C/25 °C) 1.318 - 1.322
Refractive index (n 20/D) 1.423 - 1.425
Free chlorine (Cl) conforms
Heavy metals (as Pb) ≤ 0.0001 %
Ethanol,2-Methyl-2-butene and volatile impurities (GC) (Ethanol) ≤ 2.0 % (v/v)
Ethanol,2-Methyl-2-butene and volatile impurities (GC) (2-Methyl-2-buten) ≤ 0.03 % (v/v)
Ethanol,2-Methyl-2-butene and volatile impurities (GC) (Carbon tetrachloride (impurity A)) ≤ 0.001 % (v/v)
Ethanol,2-Methyl-2-butene and volatile impurities (GC) (Chloroform (impurity B)) ≤ 0.005 % (v/v)
Ethanol,2-Methyl-2-butene and volatile impurities (GC) (Total of impurities other than ethanol and 2-methyl-2-butene) ≤ 0.1 % (v/v)
Ethanol,2-Methyl-2-butene and volatile impurities (GC)(reportingthreshold) ≤ 0.005 % (v/v)
1,1-Dichloroethene (GC) ≤ 0.03 %
1,2-Dichloroethene (GC) ≤ 0.03 %
Other residual solvents (ICH Q3C) excluded by manufacturing process
Evaporation residue ≤ 0.002 %
Water ≤ 0.020 %
Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present.
The product is stabilized with about 50 ppm 2-Methyl-2-butene.
Conforms to Ph Eur, BP, NF
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