| Specifications | |
|---|---|
| Assay (GC) | ≥ 99.5 % |
| Identity (IR) | conforms |
| Identity B (USP) | conforms |
| Identity (JP) | conforms |
| Appearance | conforms |
| Clarity of solution | conforms |
| Acidity or alkalinity | conforms |
| Acidity | conforms |
| Refractive index (n 20/D) | 1.376 - 1.378 |
| Density (d 20 °C/20 °C) | 0.785 - 0.788 |
| Density (d 25 °C/25 °C) | 0.783 - 0.787 |
| Boiling range (81-83°C) | ≥ 94 % (v/v) |
| Absorbance (at 230 nm) | ≤ 0.300 |
| Absorbance (at 250 nm) | ≤ 0.100 |
| Absorbance (at 270 nm) | ≤ 0.030 |
| Absorbance (at 290 nm) | ≤ 0.020 |
| Absorbance (at 310 nm) | ≤ 0.010 |
| The spectrum shows a steadily descending curve with no observable peaks or shoulders | conforms |
| Peroxides | conforms |
| Volatile Impurities (GC) (individual) | ≤ 0.1 % (v/v) |
| Volatile Impurities (GC) (total) | ≤ 1.0 % (v/v) |
| Benzene and related substances (GC) (Benzene) | ≤ 2 ppm |
| Benzene and related substances (GC) (total of impurities apart from 2-butanol) | ≤ 0.3 % |
| Cyclohexane (GC) | ≤ 50 ppm |
| Acetone (GC) | ≤ 50 ppm |
| Ethanol (GC) | ≤ 50 ppm |
| 1-Propylalcohol (GC) | ≤ 50 ppm |
| Isopropylether (GC) | ≤ 0.01 % |
| Other residual solvents (ICH Q3C) | excluded by manufacturing process |
| Evaporation residue | ≤ 0.0020 % |
| Water | ≤ 0.20 % |
| Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present. Conforms to Ph Eur, BP, JP, USP |
|
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Key Spec Table
| CAS # | EC Number | Hill Formula | Chemical Formula | Molar Mass | Grade Value |
|---|---|---|---|---|---|
| 67-63-0 | 200-661-7 | C₃H₈O | CH₃CH(OH)CH₃ | 60.1 g/mol | Ph Eur,BP,JP,USP |
| Description | |
|---|---|
| Catalogue Number | 100995 |
| Synonyms | Isopropyl alcohol, Isopropanol, iso-Propanol, IPA |
| Product Information | |
|---|---|
| CAS number | 67-63-0 |
| EC index number | 603-117-00-0 |
| EC number | 200-661-7 |
| Grade | Ph Eur,BP,JP,USP |
| Hill Formula | C₃H₈O |
| Chemical formula | CH₃CH(OH)CH₃ |
| Molar Mass | 60.1 g/mol |
| HS Code | 2905 12 00 |
| Structure formula Image | |
| Applications | |
|---|---|
| Application | 2-Propanol suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP. 2-Propanol CAS No. 67-63-0, EC Number 200-661-7. 2-Propanol MSDS (material safety data sheet) or SDS here. |
| Physicochemical Information | |
|---|---|
| Boiling point | 82.4 °C (1013 hPa) |
| Density | 0.786 g/cm3 (20 °C) |
| Explosion limit | 2 - 13.4 %(V) |
| Flash point | 12 °C |
| Ignition temperature | 425 °C |
| Melting Point | -89.5 °C |
| Vapor pressure | 43 hPa (20 °C) |
| Toxicological Information | |
|---|---|
| LD 50 oral | LD50 Rat 5045 mg/kg |
| LD 50 dermal | LD50 Rabbit 12800 mg/kg |
| Safety Information according to GHS | |
|---|---|
| Hazard Pictogram(s) |   |
| Hazard Statement(s) | H225: Highly flammable liquid and vapour. H319: Causes serious eye irritation. H336: May cause drowsiness or dizziness. |
| Precautionary Statement(s) | P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P240: Ground/bond container and receiving equipment. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. |
| RTECS | NT8050000 |
| Storage class | 3 Flammable liquids |
| WGK | WGK 1 slightly water endangering |
| Disposal | 1 Strongly contaminated halogen-free organic solvents: container A. |
| Safety Information | |
|---|---|
| Hazard Symbols |  Flammable Irritant |
| Categories of danger | highly flammable, irritant |
| R Phrase | R 11-36-67 Highly flammable.Irritating to eyes.Vapours may cause drowsiness and dizziness. |
| S Phrase | S 7-16-24/25-26 Keep container tightly closed.Keep away from sources of ignition - No smoking.Avoid contact with skin and eyes.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Storage and Shipping Information | |
|---|---|
| Storage | Store at +5°C to +30°C. |
| Transport Information | |
|---|---|
| Declaration (railroad and road) ADR, RID | UN 1219 , 3, II |
| Declaration (transport by air) IATA-DGR | UN 1219 , 3, II |
| Declaration (transport by sea) IMDG-Code | UN 1219 , 3, II |
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