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2-Propanol

2-suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP. 2-Propanol CAS No. 67-63-0, EC Number 200-661-7.
Code: 1009952500
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2-suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP. 2-Propanol CAS No. 67-63-0, EC Number 200-661-7.

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
67-63-0 200-661-7 C₃H₈O CH₃CH(OH)CH₃ 60.1 g/mol Ph Eur,BP,JP,USP
Description
Catalogue Number 100995
Synonyms Isopropyl alcohol, Isopropanol, iso-Propanol, IPA
Product Information
CAS number 67-63-0
EC index number 603-117-00-0
EC number 200-661-7
Grade Ph Eur,BP,JP,USP
Hill Formula C₃H₈O
Chemical formula CH₃CH(OH)CH₃
Molar Mass 60.1 g/mol
HS Code 2905 12 00
Structure formula Image
Applications
Application 2-Propanol suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP. 2-Propanol CAS No. 67-63-0, EC Number 200-661-7. 2-Propanol MSDS (material safety data sheet) or SDS here.
Physicochemical Information
Boiling point 82.4 °C (1013 hPa)
Density 0.786 g/cm3 (20 °C)
Explosion limit 2 - 13.4 %(V)
Flash point 12 °C
Ignition temperature 425 °C
Melting Point -89.5 °C
Vapor pressure 43 hPa (20 °C)
Toxicological Information
LD 50 oral LD50 Rat 5045 mg/kg
LD 50 dermal LD50 Rabbit 12800 mg/kg
Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s) H225: Highly flammable liquid and vapour.
H319: Causes serious eye irritation.
H336: May cause drowsiness or dizziness.
Precautionary Statement(s) P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P240: Ground/bond container and receiving equipment.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
RTECS NT8050000
Storage class 3 Flammable liquids
WGK WGK 1 slightly water endangering
Disposal 1
Strongly contaminated halogen-free organic solvents: container A.
Safety Information
Hazard Symbols Flammable
Irritant
Categories of danger highly flammable, irritant
R Phrase R 11-36-67
Highly flammable.Irritating to eyes.Vapours may cause drowsiness and dizziness.
S Phrase S 7-16-24/25-26
Keep container tightly closed.Keep away from sources of ignition - No smoking.Avoid contact with skin and eyes.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Storage and Shipping Information
Storage Store at +5°C to +30°C.
Transport Information
Declaration (railroad and road) ADR, RID UN 1219 , 3, II
Declaration (transport by air) IATA-DGR UN 1219 , 3, II
Declaration (transport by sea) IMDG-Code UN 1219 , 3, II
Specifications
Assay (GC) ≥ 99.5 %
Identity (IR) conforms
Identity B (USP) conforms
Identity (JP) conforms
Appearance conforms
Clarity of solution conforms
Acidity or alkalinity conforms
Acidity conforms
Refractive index (n 20/D) 1.376 - 1.378
Density (d 20 °C/20 °C) 0.785 - 0.788
Density (d 25 °C/25 °C) 0.783 - 0.787
Boiling range (81-83°C) ≥ 94 % (v/v)
Absorbance (at 230 nm) ≤ 0.300
Absorbance (at 250 nm) ≤ 0.100
Absorbance (at 270 nm) ≤ 0.030
Absorbance (at 290 nm) ≤ 0.020
Absorbance (at 310 nm) ≤ 0.010
The spectrum shows a steadily descending curve with no observable peaks or shoulders conforms
Peroxides conforms
Volatile Impurities (GC) (individual) ≤ 0.1 % (v/v)
Volatile Impurities (GC) (total) ≤ 1.0 % (v/v)
Benzene and related substances (GC) (Benzene) ≤ 2 ppm
Benzene and related substances (GC) (total of impurities apart from 2-butanol) ≤ 0.3 %
Cyclohexane (GC) ≤ 50 ppm
Acetone (GC) ≤ 50 ppm
Ethanol (GC) ≤ 50 ppm
1-Propylalcohol (GC) ≤ 50 ppm
Isopropylether (GC) ≤ 0.01 %
Other residual solvents (ICH Q3C) excluded by manufacturing process
Evaporation residue ≤ 0.0020 %
Water ≤ 0.20 %
Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present.
Conforms to Ph Eur, BP, JP, USP
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