| Specifications | |
|---|---|
| Purity (GC) | ≥ 99.5 % |
| Assay (acidimetric) | 99.0 - 100.5 % |
| Identity (IR) | conforms |
| Appearance of solution | conforms |
| Acidity (Ph Eur, BP) | conforms |
| Acidity (NF) | conforms |
| Density (d 20 °C/20 °C) | 0.898 - 0.902 |
| Density (d 25 °C/25 °C) | 0.894 - 0.898 |
| Refractive index (n 20/D) | 1.370 - 1.373 |
| Methyl compounds (GC) | conforms |
| Related substances (GC) | ≤ 0.2 % |
| Residual solvents class 3 (ICH Q3C) | < 0.5 |
| Readily carbonizable substances | conforms |
| Evaporation residue | ≤ 0.0030 % |
| Water | ≤ 0.10 % |
| Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present. Conforms to Ph Eur, BP, NF |
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Key Spec Table
| CAS # | EC Number | Hill Formula | Chemical Formula | Molar Mass | Grade Value |
|---|---|---|---|---|---|
| 141-78-6 | 205-500-4 | C₄H₈O₂ | CH₃COOC₂H₅ | 88.11 g/mol | Ph Eur,BP,NF |
| Description | |
|---|---|
| Catalogue Number | 100864 |
| Synonyms | Ethyl ethanoate, Acetic ester, Ethyl ester |
| Description | Ethyl acetate |
| Product Information | |
|---|---|
| CAS number | 141-78-6 |
| EC index number | 607-022-00-5 |
| EC number | 205-500-4 |
| Grade | Ph Eur,BP,NF |
| Hill Formula | C₄H₈O₂ |
| Chemical formula | CH₃COOC₂H₅ |
| Molar Mass | 88.11 g/mol |
| HS Code | 2915 31 00 |
| Structure formula Image | |
| Applications | |
|---|---|
| Application | Ethyl acetate suitable for use as excipient EMPROVE® exp Ph Eur,BP,NF. CAS 141-78-6, EC Number 205-500-4, chemical formula CH₃COOC₂H₅. Ethyl acetate MSDS (material safety data sheet) or SDS, storage and handling info here. Synonyms: Ethyl ethanoate, Acetic ester, Ethyl ester |
| Physicochemical Information | |
|---|---|
| Boiling point | 77 °C (1013 hPa) |
| Density | 0.90 g/cm3 (20 °C) |
| Explosion limit | 2.1 - 11.5 %(V) |
| Flash point | -4 °C |
| Ignition temperature | 460 °C |
| Melting Point | -83 °C |
| Vapor pressure | 97 hPa (20 °C) |
| Solubility | 85.3 g/l |
| Toxicological Information | |
|---|---|
| LD 50 oral | LD50 Rat 5620 mg/kg |
| LD 50 dermal | LD50 Rabbit > 18000 mg/kg |
| Safety Information according to GHS | |
|---|---|
| Hazard Pictogram(s) |   |
| Hazard Statement(s) | H225: Highly flammable liquid and vapour. H319: Causes serious eye irritation. H336: May cause drowsiness or dizziness. EUH066: Repeated exposure may cause skin dryness or cracking. |
| Precautionary Statement(s) | P210: Keep away from heat/sparks/open flames/hot surfaces. No smoking. P240: Ground/bond container and receiving equipment. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. |
| RTECS | AH5425000 |
| Storage class | 3 Flammable liquids |
| WGK | WGK 1 slightly water endangering |
| Disposal | 1 Strongly contaminated halogen-free organic solvents: container A. |
| Safety Information | |
|---|---|
| Hazard Symbols |  Flammable Irritant |
| Categories of danger | highly flammable, irritant |
| R Phrase | R 11-36-66-67 Highly flammable.Irritating to eyes.Repeated exposure may cause skin dryness or cracking.Vapours may cause drowsiness and dizziness. |
| S Phrase | S 16-26-33 Keep away from sources of ignition - No smoking.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Take precautionary measures against static discharges. |
| Storage and Shipping Information | |
|---|---|
| Storage | Store at +15°C to +25°C. |
| Transport Information | |
|---|---|
| Declaration (railroad and road) ADR, RID | UN 1173 , 3, II |
| Declaration (transport by air) IATA-DGR | UN 1173 , 3, II |
| Declaration (transport by sea) IMDG-Code | UN 1173 , 3, II |
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